{"id":905,"date":"2020-10-13T11:00:05","date_gmt":"2020-10-13T02:00:05","guid":{"rendered":"http:\/\/ken-takahashi.net\/?p=905"},"modified":"2025-03-15T13:12:21","modified_gmt":"2025-03-15T04:12:21","slug":"video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes","status":"publish","type":"post","link":"https:\/\/ken-takahashi.net\/ja\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/","title":{"rendered":"\u30d3\u30c7\u30aa\u516c\u958b\uff1a\u30d2\u30c8\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306eiPS\u7d30\u80de\u30e2\u30c7\u30eb"},"content":{"rendered":"<h4>Summary<\/h4>\n\n\n\n<ol><li>\u30d2\u30c8iPS\u7d30\u80de\u304b\u3089\u4f5c\u3063\u305f\u5fc3\u7b4b\u7d30\u80de\u3092\u7528\u3044\u3066\u3001\u865a\u8840\u6027\u5fc3\u75be\u60a3\u30e2\u30c7\u30eb\u306e\u65b0\u305f\u306a\u4f5c\u51fa\u65b9\u6cd5\u3092\u958b\u767a\u3057\u3001\u305d\u306e\u624b\u9806\u306e\u52d5\u753b\u3092\u30d3\u30c7\u30aa\u30b8\u30e3\u30fc\u30ca\u30eb\u3067\u767a\u8868\u3057\u307e\u3057\u305f\u3002<\/li><li>\u5f93\u6765\u3088\u308a\u3082\u7c21\u4fbf\u306b\u5fc3\u81d3\u865a\u8840\u30e2\u30c7\u30eb\u304c\u4f5c\u51fa\u53ef\u80fd\u306a\u624b\u6cd5\u3067\u3042\u308a\u3001\u307e\u305f\u5f93\u6765\u306e\u8a8c\u9762\u3067\u306f\u4f1d\u308f\u308a\u306b\u304f\u304b\u3063\u305f\u64cd\u4f5c\u3084\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u89e3\u6790\u6cd5\u3092\u3001\u52d5\u753b\u3067\u5177\u4f53\u7684\u306b\u308f\u304b\u308a\u3084\u3059\u304f\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\u3002<\/li><li>\u3053\u306e\u30e2\u30c7\u30eb\u306b\u3088\u3063\u3066\u3001\u865a\u8840\u6027\u75be\u60a3\u306e\u85ac\u306e\u958b\u767a\u3084\u5fc3\u7b4b\u6897\u585e\u306e\u539f\u56e0\u89e3\u660e\u304c\u4fc3\u9032\u3055\u308c\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/li><\/ol>\n\n\n\n<p class=\" translation-block\">\u5ca1\u5c71\u5927\u5b66\u306e\u9ad8\u6a4b\u8ce2\u7814\u7a76\u51c6\u6559\u6388\u306f5\u67085\u65e5\u3001\u30d2\u30c8iPS\u7d30\u80de\u304b\u3089\u5206\u5316\u3057\u305f\u5fc3\u7b4b\u7d30\u80de\u3092\u7528\u3044\u3066\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u75c5\u614b\u30e2\u30c7\u30eb\u3092\u767a\u8868\u3057\u307e\u3057\u305f(<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X19318571?viaihub\" target=\"_self\"><em>Biochem Biophys Res Commun<\/em>\u00a02019, 520(3): 600-605<\/a>)\u3002\u3053\u306e\u5b9f\u9a13\u65b9\u6cd5\u306e\u52d5\u753b\u304c\u672c\u65e5\u3001\u7c73\u56fd\u306e\u79d1\u5b66\u30d3\u30c7\u30aa\u30b8\u30e3\u30fc\u30ca\u30eb\u300cJournal of Visualized Experiments\u300d\u3067\u4e00\u822c\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<iframe allowtransparency=\"true\" allow=\"encrypted-media *\" allowfullscreen=\"\" height=\"570\" width=\"460\" border=\"0\" scrolling=\"no\" frameborder=\"0\" marginwheight=\"0\" marginwidth=\"0\" src=\"https:\/\/www.jove.com\/embed\/player?id=61104&amp;access=8tfq3lk95b&amp;t=1&amp;a=1&amp;s=1&amp;fpv=1\"><p><a title=\"Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived Cardiomyocytes\" href=\"https:\/\/www.jove.com\/v\/61104\/model-ischemic-heart-disease-video-based-comparison-cardiomyocyte\">Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived Cardiomyocytes<\/a><\/p><\/iframe>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30d2\u30c8iPS\u7d30\u80de\u304b\u3089\u5fc3\u7b4b\u7d44\u7e54\u3092\u4f5c\u308b\u65b9\u6cd5\u306f\u3001\u9ad8\u5ea6\u306a\u6280\u8853\u3068\u591a\u5927\u306a\u52b4\u529b\u304c\u5fc5\u8981\u306a\u305f\u3081\u3001\u666e\u53ca\u306b\u554f\u984c\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u4eca\u56de\u958b\u767a\u3055\u308c\u305f\u65b9\u6cd5\u306f\u3001iPS\u7d30\u80de\u304b\u3089\u5fc3\u7b4b\u3078\u306e\u5206\u5316\u8a98\u5c0e\u3068\u3001\u865a\u8840\u306b\u3088\u308b\u5fc3\u7b4b\u30c0\u30e1\u30fc\u30b8\u306e\u8a98\u767a\u3092\u6bd4\u8f03\u7684\u5bb9\u6613\u306b\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u306e\u65b9\u6cd5\u306e\u666e\u53ca\u306b\u3088\u308a\u3001\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u85ac\u306e\u958b\u767a\u3084\u3001\u5fc3\u7b4b\u6897\u585e\u306e\u75c5\u614b\u89e3\u660e\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote\"><p>iPS\u7d30\u80de\u304b\u3089\u30d2\u30c8\u306e\u75c5\u6c17\u306e\u30e2\u30c7\u30eb\u3092\u958b\u767a\u3059\u308b\u7814\u7a76\u306f\u3001\u4eca\u5f8c\u3082\u307e\u3059\u307e\u3059\u767a\u5c55\u304c\u671f\u5f85\u3055\u308c\u308b\u5206\u91ce\u3067\u3059\u3002<\/p><p>\u3053\u308c\u304b\u3089\u306e\u7814\u7a76\u3092\u62c5\u3046\u5b66\u751f\u3055\u3093\u3001\u5171\u540c\u7814\u7a76\u3092\u3054\u691c\u8a0e\u3044\u305f\u3060\u3051\u308b\u5148\u751f\u65b9\u3001\u307e\u305f\u3054\u95a2\u5fc3\u3092\u6301\u3063\u3066\u3044\u305f\u3060\u3051\u308b\u4e00\u822c\u306e\u7686\u69d8\u306e\u3001\u3055\u3089\u306a\u308b\u3054\u652f\u63f4\u3092\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u3044\u305f\u3057\u307e\u3059\u3002<\/p><cite>\u9ad8\u6a4b \u8ce2<\/cite><\/blockquote>\n\n\n\n<p class=\" translation-block\">\u672c\u7814\u7a76\u306fJSPS\u79d1\u7814\u8cbb\u30fb\u56fd\u969b\u5171\u540c\u7814\u7a76\u52a0\u901f\u57fa\u91d1(\u56fd\u969b\u5171\u540c\u7814\u7a76\u5f37\u5316)<a href=\"https:\/\/kaken.nii.ac.jp\/grant\/KAKENHI-PROJECT-17KK0168\" target=\"_blank\" rel=\"noreferrer noopener\">17KK0168<\/a>\u306e\u52a9\u6210\u3092\u53d7\u3051\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u95a2\u9023\u8a18\u4e8b: <a href=\"https:\/\/www.okayama-u.ac.jp\/up_load_files\/ebulletin-RUs\/pdf\/vol83.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Skipping a beat \u2014 a novel method to study heart attacks<\/a><\/p>\n\n\n\n<p>\u95a2\u9023\u8a18\u4e8b: <a href=\"https:\/\/ken-takahashi.net\/ja\/filming-for-jove-the-top-video-science-journal\/\">\u4e00\u6d41\u30d3\u30c7\u30aa\u79d1\u5b66\u8a8cJoVE\u306e\u30d3\u30c7\u30aa\u64ae\u5f71<\/a><\/p>\n\n\n\n<p>\u95a2\u9023\u8a18\u4e8b: <a href=\"https:\/\/ken-takahashi.net\/ja\/heart-attack-modeled-with-human-stem-cells\/\">Heart attack modeled with human stem cells<\/a><\/p>\n\n\n\n<p>* * *<\/p>\n\n\n\n<p><strong>Takahashi Lab<\/strong>&nbsp;at Okayama University uses principles of physiology, cellular and molecular biology, and biophysics. The purpose of the lab is to develop science and medicine by unveiling the mechanisms of diseases through collaborations with scientists, epidemiologists, and corporate alliances. The alliance includes Harvard University, Boston University, Tokyo University of Science, and PD Aerospace, Ltd.<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5ca1\u5c71\u5927\u5b66\u306e\u9ad8\u6a4b\u8ce2\u7814\u7a76\u51c6\u6559\u6388\u306f5\u67085\u65e5\u3001\u30d2\u30c8iPS\u7d30\u80de\u304b\u3089\u5206\u5316\u3057\u305f\u5fc3\u7b4b\u7d30\u80de\u3092\u7528\u3044\u3066\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u75c5\u614b\u30e2\u30c7\u30eb\u3092\u767a\u8868\u3057\u307e\u3057\u305f(Biochem Biophys Res Commun 2019, 520(3): 600-605)\u3002\u3053\u306e\u5b9f\u9a13\u65b9\u6cd5\u306e\u52d5\u753b\u304c\u672c\u65e5\u3001\u7c73\u56fd\u306e\u79d1\u5b66\u30d3\u30c7\u30aa\u30b8\u30e3\u30fc\u30ca\u30eb\u300cJournal of Visualized Experiments\u300d\u3067\u4e00\u822c\u516c\u958b\u3055\u308c... <br \/> <a class=\"read-more\" href=\"https:\/\/ken-takahashi.net\/ja\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>","protected":false},"author":1,"featured_media":911,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[35,34,28,39],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v15.9.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Video released: model for human ischemic heart disease - Ken Takahashi<\/title>\n<meta name=\"description\" content=\"We published a video article about the model of ischemic heart disease using heart cells made from human iPS cells.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ken-takahashi.net\/ja\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Video released: model for human ischemic heart disease - Ken Takahashi\" \/>\n<meta property=\"og:description\" content=\"We published a video article about the model of ischemic heart disease using heart cells made from human iPS cells.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ken-takahashi.net\/ja\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/\" \/>\n<meta property=\"og:site_name\" content=\"Ken Takahashi\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-13T02:00:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-15T04:12:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ken-takahashi.net\/wp-content\/uploads\/2020\/10\/JoVE-1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"939\" \/>\n\t<meta property=\"og:image:height\" content=\"527\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\">\n\t<meta name=\"twitter:data1\" content=\"2\u5206\">\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebSite\",\"@id\":\"http:\/\/ken-takahashi.net\/#website\",\"url\":\"http:\/\/ken-takahashi.net\/\",\"name\":\"Ken Takahashi\",\"description\":\"\\u9ad8\\u6a4b \\u8ce2\",\"publisher\":{\"@id\":\"http:\/\/ken-takahashi.net\/#\/schema\/person\/7cb56aa2c81620fa7cab23e6c80c91df\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":\"http:\/\/ken-takahashi.net\/?s={search_term_string}\",\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"ja\"},{\"@type\":\"ImageObject\",\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#primaryimage\",\"inLanguage\":\"ja\",\"url\":\"https:\/\/ken-takahashi.net\/wp-content\/uploads\/2020\/10\/JoVE-1.png\",\"width\":939,\"height\":527,\"caption\":\"JoVE video - Ken Takahashi\"},{\"@type\":\"WebPage\",\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#webpage\",\"url\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/\",\"name\":\"Video released: model for human ischemic heart disease - Ken Takahashi\",\"isPartOf\":{\"@id\":\"http:\/\/ken-takahashi.net\/#website\"},\"primaryImageOfPage\":{\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#primaryimage\"},\"datePublished\":\"2020-10-13T02:00:05+00:00\",\"dateModified\":\"2025-03-15T04:12:21+00:00\",\"description\":\"We published a video article about the model of ischemic heart disease using heart cells made from human iPS cells.\",\"breadcrumb\":{\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#breadcrumb\"},\"inLanguage\":\"ja\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"item\":{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ken-takahashi.net\/\",\"url\":\"https:\/\/ken-takahashi.net\/\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"position\":2,\"item\":{\"@type\":\"WebPage\",\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/\",\"url\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/\",\"name\":\"Video released: Model for ischemic heart disease with human iPS cardiomyocytes\"}}]},{\"@type\":\"Article\",\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#article\",\"isPartOf\":{\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#webpage\"},\"author\":{\"@id\":\"http:\/\/ken-takahashi.net\/#\/schema\/person\/7cb56aa2c81620fa7cab23e6c80c91df\"},\"headline\":\"Video released: Model for ischemic heart disease with human iPS cardiomyocytes\",\"datePublished\":\"2020-10-13T02:00:05+00:00\",\"dateModified\":\"2025-03-15T04:12:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#webpage\"},\"publisher\":{\"@id\":\"http:\/\/ken-takahashi.net\/#\/schema\/person\/7cb56aa2c81620fa7cab23e6c80c91df\"},\"image\":{\"@id\":\"http:\/\/ken-takahashi.net\/video-released-model-for-ischemic-heart-disease-with-human-ips-cardiomyocytes\/#primaryimage\"},\"keywords\":\"cardiology,heart disease,myocardial infarction,regenerative medicine\",\"articleSection\":\"Research\",\"inLanguage\":\"ja\"},{\"@type\":[\"Person\",\"Organization\"],\"@id\":\"http:\/\/ken-takahashi.net\/#\/schema\/person\/7cb56aa2c81620fa7cab23e6c80c91df\",\"name\":\"takahashy\",\"image\":{\"@type\":\"ImageObject\",\"@id\":\"http:\/\/ken-takahashi.net\/#personlogo\",\"inLanguage\":\"ja\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/30b95f3829b13cd3a75b55133f7dae64?s=96&d=mm&r=g\",\"caption\":\"takahashy\"},\"logo\":{\"@id\":\"http:\/\/ken-takahashi.net\/#personlogo\"},\"sameAs\":[\"http:\/\/ken-takahashi.net\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","_links":{"self":[{"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/posts\/905"}],"collection":[{"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/comments?post=905"}],"version-history":[{"count":17,"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/posts\/905\/revisions"}],"predecessor-version":[{"id":1198,"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/posts\/905\/revisions\/1198"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/media\/911"}],"wp:attachment":[{"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/media?parent=905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/categories?post=905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ken-takahashi.net\/ja\/wp-json\/wp\/v2\/tags?post=905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}