高橋 賢

Category: Research

Wyss Institute Retreat 2019

Event: Wyss Institute Retreat Date: November 22, 2019 Location: Boston, USA Wyss Institute for Biologically Inspired Engineering, Harvard University, holds its annual retreat every year. It is a day-long meeting that brings together all members of the Institute community including faculty, researchers, technical and administrative staff, fellows, clinical collaborators, and students. The agenda gives the…
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Heart attack modeled with human stem cells

Toward the development of individual model of ischemic heart disease Heart attack caused by ischemia is a major medical problem that threatens our healthy life. Researchers at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences developed a model of myocardial infarction using cardiomyocytes differentiated from human induced pluripotent stem cells. The journal Biochemical and…
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Promoting Mechanobiology

Ken Takahashi was inaugurated as Associate Editor of Mechanobiology Journal on Sunday September 22, 2019. The goal of the journal is to improve the understanding of mechanobiology and ultimately provide approaches to translate into therapeutic strategies and rectifying husbandry and agricultural problems. Ken contributed to hold 2nd International Symposium on Mechanobiology in 2014 as Secretary General, and…
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Unravel the mechanism of joint pain

The joint fluids of patients with osteoarthritis contain elevated levels of inflammatory cytokines. These cytokines induce the expression of proteases in cartilage cells, which will lead to progress of joint destruction. Dr. Ohtsuki found that mechanical strain attenuates inflammatory cytokine-induced expression of matrix-degrading enzymes, which was published in Experimental Cell Research journal. According to the…
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Reviewer certificate gallery

Peer review is the cornerstone of science. Ken Takahashi contributes to the development of science and medicine by peer-reviewing research manuscripts. A gallery of the reviewer certificates was created to showcase the peer review works of Ken Takahashi.Site: https://ken-takahashi.net/?page_id=478 Related: Ken Takahashi’s Publon profile * * * Takahashi Lab at Okayama University uses principles of physiology,…
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Presentations are available at LinkedIn SlideShare

Ken Takahashi’s presentations are now available at LinkedIn Slideshare. Visit https://www.slideshare.net/KenTakahashi19 and see his works! Related: Outstanding Research Award in IC-LYMS2019 in Taipei * * * Takahashi Lab at Okayama University uses principles of physiology, cellular and molecular biology, and biophysics. The purpose of the lab is to develop science and medicine by unveiling the mechanisms…
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Peer review: effect of microgravity on the development of zebrafish heart

A space biology article, on which Ken Takahashi performed peer review, was published in Journal of Biomechanics. This article will give a clue to understand the effect of gravity on the development of cardiovascular system. Effect of Simulated Microgravity Induced PI3K-nos2b Signalling on Zebrafish Cardiovascular Plexus Network Formation Related: Reviewer certificate gallery * * *…
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Peer review: cell stretch systems for studies of cardiac mechano-signaling

A mechanobiology article, on which Ken Takahashi performed peer review, was published in Frontiers in Bioengineering and Biotechnology journal. This article will help understanding methodology used in mechanobiology study. Stretch in Focus: 2D in-planar cell stretch systems for studies of cardiac mechano-signaling Related: Reviewer certificate gallery ### Takahashi Lab at Okayama University uses principles of physiology,…
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Outstanding Research Award at ICBMS 2019

Ken Takahashi received the Outstanding Research Award at 2019 International Conference on Biology and Medical Science (ICBMS 2019) held in Okinawa, Japan during Feb 28 – Mar 03 2019. The title of the lecture was “Mechanobiology and its application to medical problem solving”. ### Takahashi Lab at Okayama University uses principles of physiology, cellular and molecular…
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How do heart cells sense they are stretched?

Heart cells sense that they are stretched when the heart is subjected to high blood pressure. But how? It is known that concentration of calcium ion in cardiomyocytes increases when they are stretched. Takahashi and co-workers found that a specific protein, L-type calcium channel, is the key to this calcium increase event using rat cardiomyocytes.…
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