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タグ: heart disease

ビデオ公開:ヒト虚血性心疾患のiPS細胞モデル

Summary Dr. Ken Takahashi of Okayama University published a video article on a model of ischemic heart disease using human iPS heart cells. The method makes it easier to create a cardiac ischemia model. The use of this model will lead to the development of drugs for ischemic heart disease and reveal the cause of myocardial infarction. On May 5, Research Associate Professor Ken Takahashi of Okayama University published an article about the model of ischemic heart disease using cardiomyocytes differentiated from human iPS cells (Biochem Biophys Res Commun 2019, 520(3): 600-605). A video for this experimental method was released to the public today in Journal of Visualized Experiments. Model of…
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研究報告2019: Heart-on-chipによる心筋梗塞時不整脈のメカニズム解明

The principal investigator, Ken Takahashi, traveled to Boston, USA from the end of July 2018, and began research at the Wyss Institute at Harvard University. His original plan was to complete the joint research at the end of July 2019 and return to Japan. Related: Joining Harvard Medical School However, Takahashi joined the “Blood-Brain Barrier Team” within the Wyss Institute, which has strong ties with industry including pharmaceutical companies. As a result of the development of the fascinating project, he extended the research period in Boston by 4 months, which led him to form a network with about 50 excellent researchers from all over the world. Common mechanism for myocardial…
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IC-LYMS2019(台北)にて優秀研究賞を受賞

Ken Takahashi received the Outstanding Research Award in 2019 International Conference for Leading and Young Medical Scientists (IC-LYMS 2019) in Taipei, Taiwan, which was organized by Asia Pacific Society for Biology and Medical Sciences. The purpose of the conference was to provide a platform for the exchange and networking between top scientists, emerging young researchers, and students across a wide spectrum of biology and medical sciences. Nineteen presentations and three posters were presented at the conference, which took place four days from 20th to 23rd December 2019. Takahashi gave a keynote lecture entitled “Ischemia-reperfusion injury” in this small, but exciting meeting. Experts from various fields including clinical pediatrics and material…
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Lab member Chen Wang received the 1st Poster prize in IC-LYMS2019

Dr. Chen Wang, PhD student in Takahashi lab, won the 1st prize in poster presentation in 2019 International Conference for Leading and Young Medical Scientists (IC-LYMS 2019) held by Asia Pacific Society for Biology and Medical Sciences in Taipei. She gave a poster presentation entitled “Roles of the TRPM4 channel in mitochondrial function, ROS generation, and calcium release in myocardial ischemia–reperfusion injury”. This study was supported by the Fund for the Promotion of Joint International Research (Fostering Joint International Research), 17KK0168. Related: Outstanding Research Award in IC-LYMS2019 in Taipei * * * Takahashi Lab at Okayama University uses principles of physiology, cellular and molecular biology, and biophysics. The purpose of the lab…
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Heart attack modeled with human stem cells

Toward the development of individual model of ischemic heart disease Heart attack caused by ischemia is a major medical problem that threatens our healthy life. Researchers at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences developed a model of myocardial infarction using cardiomyocytes differentiated from human induced pluripotent stem cells. The journal Biochemical and Biophysical Research Communications published the study, with Ken Takahashi, Ph.D., as corresponding author, and Wei Heng, MSc., a graduate student in the Naruse Lab, as first author. To date, laboratory animals such as mouse have been used to model diseases including myocardial infarction. However, there have been concerns about difference in characteristics of cardiomyocytes e.g. heart…
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